You may be able to help protect your home from a sewer backup by taking the following preventive measures, according to the III:

Install a backup water valve: A licensed plumber can install a water valve in sewer or drain lines. This valve lets sewage water flow out of the pipes, but not back in.
Properly dispose of household waste: Items like paper towels do not decompose quickly and can contribute to clogged sewer lines if they are flushed down a toilet. And in the kitchen, be sure to properly dispose of cooking grease — if you pour it down the sink, it can solidify in the pipes.
Inspect and trim tree roots: If you have noticeable tree roots throughout your yard, you may need to have a professional trim them back to help lessen the risk of them growing into a sewer line.

While these safety measures can help minimize the risk of a sewer backup occurring at your home, it's important to remember that sewer backups aren't typically covered by a standard homeowners insurance policy. To further protect your home, consider adding water backup coverage to your homeowners insurance policy which may help pay for repairs after a sewer backup.